for separation sciences


Welcome to the website of the Chemometrics & Advanced Separations Team (CAST) of Bob Pirok and Saer Samanipour, with researchers from the University of Amsterdam and VU University Amsterdam. The team comprises enthusiastic researchers from both universities who devote a bit of their time to developing guides and tools for use by the community. Here, you will be able to find useful, information, software and tools for use in mass spectrometry and (multi-dimensional) chromatography.

News and Updates


Peak Tracking for Use in 2D-LC

Working with comprehensive 2D-LC (LC×LC) data can be highly challenging. This is particularly true for complex samples. Together with the group of Dwight Stoll, Stef Molenaar developed a pack-tracking algorithm to solve this.

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Register now for SCM-X!

Every other year, the combined analytical chemistry groups of the University of Amsterdam and VU University Amsterdam organize the International Symposium on the Separation and

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Recent applications of retention modelling in LC

PhD candidate Mimi den Uijl has together with her co-workers reviewed recent applications of retention modelling in LC. In the review, den Uijl furthermore identified key application areas where retention modelling received a significant degree of interest.

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Detection Challenges in Polymer Analysis with LC

What are the latest developments around detection techniques for (polymer) LC? Where are the opportunities? Our talented PhD candidate and colleague Wouter Knol answers these and more questions in his open-access review published in Journal of Separation Sciences together with polymer expert Prof. Ron Peters.

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Method Database

We maintain a searchable database containing all 2D-LC methods published since the 1978 paper by Erni and Frei. The database, which contains over 550 methods, is part of a collaboration between the University of Amsterdam (Pirok) and Gustavus Adolphus College (Stoll).